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Inflammation and Lung Cancer [electronic resource] / edited by Steven M. Dubinett. - X, 212 p. 5 illus., 3 illus. in color. online resource.

Inflammation and Lung Cancer: The relationship to COPD -- Inflammation and Lung Cancer: The role of EMT -- Inflammation and Lung Cancer: Molecular pathology -- Inflammation and Lung Cancer: Prevention -- Inflammation and Lung Cancer: The Link to Angiogenesis -- Inflammation and Lung Cancer: Eicosanoids -- Inflammation and Lung Cancer: Addressing Inflammation with Immunotherapy.

This volume  presents aspects of the inflammatory tumor microenvironment (TME) and its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of microRNAs (miRNAs), and an increase in a stem cell phenotype. The volume also covers the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non-small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion, and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.

ISBN: 9781493927241

Standard No.: 10.1007/978-1-4939-2724-1 doi

Subjects--Topical Terms:
Medicine.
Cancer research.
Immunology.
Medical microbiology.
Pathology.
Biomedicine.
Cancer Research.
Pathology.
Medical Microbiology.
Immunology.

LC Class. No.: RC261-271

Dewey Class. No.: 614.5999