MARC details
| 000 -LEADER |
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04313nam a22005175i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-319-02591-9 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20160405110544.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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140527s2014 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783319025919 |
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978-3-319-02591-9 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-319-02591-9 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RB155-155.8 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QH431 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MFN |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED107000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
611.01816 |
| Edition number |
23 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
599.935 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Hormones, Intrauterine Health and Programming |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Jonathan R Seckl, Yves Christen. |
| 264 #1 - |
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Cham : |
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Springer International Publishing : |
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Imprint: Springer, |
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2014. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
XIV, 189 p. 10 illus., 9 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - |
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text |
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txt |
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rdacontent |
| 337 ## - |
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computer |
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c |
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rdamedia |
| 338 ## - |
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online resource |
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cr |
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rdacarrier |
| 347 ## - |
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text file |
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PDF |
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rda |
| 490 1# - SERIES STATEMENT |
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| Series statement |
Research and Perspectives in Endocrine Interactions, |
| International Standard Serial Number |
1861-2253 ; |
| Volume number/sequential designation |
12 |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Foreword -- Early growth and later health: findings from the Helsinki Birth Cohort Study by Johan G. Eriksson -- Male and female placentas have divergent transcriptomic and epigenomic responses to maternal diets: not just hormones by Anne Gabory, Alexandre Vigé, Jean Lesage, Isabelle Fajardy, Laure Ferry, Linda Attig, Anne Vambergue, Didier Vieau, Jean-Philippe Jais, Luc Jouneau, and Claudine Junien -- Glucocorticoids and fetal programming; necessary and sufficient? By Jonathan R. Seckl -- Developmental programming and the placenta: focusing in on glucocorticoids by Caitlin S. Wyrwoll -- Maternal stress and in utero programming by Louise C. Kenny, Claire Everard and Ali S. Khashan -- Developmental epigenetics and risks of later non-communicable disease by M.A. Hanson, P.D. Gluckman and K.M. Godfrey -- Epigenetic effects of extreme intrauterine growth in humans by John M. Greally -- The Role of the Placenta in Fetal Programming by John Challis, Debora Sloboda, Shaofu Li, Thorsten Braun, Frank Bloomfield, Ghazala Begum, Anne White, Felice Petraglia, John Newnham -- Developmental Origins of Diabetes: The Role of Epigenetics by Rebecca A. Simmons -- Glucocorticoids, programming and the transmission of effects across generations by Amanda J. Drake -- Subject index. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
The environment of the fetus in the womb is emerging as a key determinant not only of its immediate status but also of the offspring’s long-term well-being. This largely started with reports of striking epidemiological associations between lower, but still normal, birth weight and a marked increase in the incidence of cardiac, metabolic and neuropsychiatric disorders from childhood to senescence. In seeking to explain these observations, collectively referred to as ‘developmental programming,’ a new subfield of biology has emerged. Major discoveries include detailing the etiological roles of maternal factors such as nutrition, inflammatory disease, stress and psychopathology. Key biochemical mediators have been discovered, notably including hormones such as glucocorticoids, which act on both the fetus and the placenta to change the trajectory of growth, tissue maturation and the expression of specific genes in affected cells. Such persisting changes in the transcription of genes may be in part underpinned by epigenetic changes. The mechanisms of these effects are beginning to emerge and offer the prospect of new diagnostics, biomarkers and potential therapeutic targets. This work provides an accessible and cutting-edge view of this rapidly emerging field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Human genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Obstetrics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Endocrinology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Human Genetics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Endocrinology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Obstetrics/Perinatology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Seckl, Jonathan R. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Christen, Yves. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Printed edition: |
| International Standard Book Number |
9783319025902 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
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| Uniform title |
Research and Perspectives in Endocrine Interactions, |
| -- |
1861-2253 ; |
| Volume number/sequential designation |
12 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/978-3-319-02591-9">http://dx.doi.org/10.1007/978-3-319-02591-9</a> |
| 912 ## - |
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ZDB-2-SBL |
