MARC details
| 000 -LEADER |
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03976nam a22005295i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-319-03725-7 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20160405110545.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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140224s2014 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783319037257 |
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978-3-319-03725-7 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-319-03725-7 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC261-271 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJCL |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED062000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
614.5999 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
MicroRNAs: Key Regulators of Oncogenesis |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Sadegh Babashah. |
| 264 #1 - |
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Cham : |
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Springer International Publishing : |
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Imprint: Springer, |
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2014. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
XXVI, 433 p. 26 illus., 21 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - |
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text |
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txt |
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rdacontent |
| 337 ## - |
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computer |
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c |
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rdamedia |
| 338 ## - |
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online resource |
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cr |
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rdacarrier |
| 347 ## - |
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text file |
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PDF |
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rda |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Preface -- Part I MicroRNAs: biology and implications in cancer -- MicroRNAs and cancer: an overview -- Epigenetics and microRNA in cancer -- MicroRNA, diet and cancer chemoprevention -- MicroRNAs and energy metabolism in cancer cells -- MicroRNAs and solid tumors -- MicroRNAs and blood cancers -- MicroRNAs and oncogenic human viruses -- MicroRNAs linking cancer and inflammation: focus on liver cancer -- MicroRNAs and regulatory pathways in tumorigenesis -- MicroRNA-modulated apoptotic and autophagic signaling networks in cancer -- MicroRNAs and cancer drug resistance and drug sensitivity -- The biological roles of microRNAs in cancer stem cells -- Part II MicroRNAs and their clinical implications -- MicroRNAs and clinical implications in cancer -- MicroRNA expression profiling and its clinical impact in breast cancer -- MicroRNAs and their clinical impact on resistance to anticancer treatment -- Nanocarriers and microRNA-based scenarios for cancer therapy -- Challenges and strategies for pulmonary delivery of microRNA-based therapeutics -- Abbreviations -- Index. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs play a momentous role in oncogenesis via regulating cell proliferation and apoptosis as oncogenes or tumour suppressors. Expression signatures of miRNAs offer exciting opportunities for crafting cutting edge strategies in the diagnosis, prognosis, and therapy of cancer. Since miRNAs can function as either oncogenes or tumor suppressor genes in the tortuous route of oncogenesis, the promise represented by using these small RNAs as therapeutic targets presents new perspectives to the landscape of cancer therapy by either inhibiting or augmenting their activity. This book devotes efforts to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of miRNAs found to be associated with cancer pathogenesis and possible mechanisms underlying the substantial roles played by miRNAs in cancer development and progression. Also, it intends to pave the way for readers to gain novel insights into using miRNAs as cancer biomarkers and therapeutic platforms. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Cancer research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Human genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Gene expression. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Medical genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Drug resistance. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Molecular biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Cancer Research. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Human Genetics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Gene Expression. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Gene Function. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Molecular Medicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Drug Resistance. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Babashah, Sadegh. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Printed edition: |
| International Standard Book Number |
9783319037240 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/978-3-319-03725-7">http://dx.doi.org/10.1007/978-3-319-03725-7</a> |
| 912 ## - |
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ZDB-2-SBL |
