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04776nam a22005295i 4500 |
| 001 - CONTROL NUMBER |
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978-81-322-2053-4 |
| 003 - CONTROL NUMBER IDENTIFIER |
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DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20160405110637.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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141020s2014 ii | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9788132220534 |
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978-81-322-2053-4 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-81-322-2053-4 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QH588.S83 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
PSAK |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
SCI017000 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
SCI049000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
571.6 |
| Edition number |
23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Ray Banerjee, Ena. |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
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| Title |
Perspectives in Regenerative Medicine |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
by Ena Ray Banerjee. |
| 264 #1 - |
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New Delhi : |
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Springer India : |
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Imprint: Springer, |
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2014. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
XIX, 152 p. 79 illus., 44 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - |
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text |
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txt |
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rdacontent |
| 337 ## - |
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computer |
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c |
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rdamedia |
| 338 ## - |
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online resource |
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cr |
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rdacarrier |
| 347 ## - |
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text file |
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PDF |
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rda |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Chapter 1 Stem Cell and its Niche -- Sub-Chapter A. Stem Cell Niche in the Lung -- Sub-Chapter B. Other Stem Cell Niches -- Sub-chapter C. Mesenchymal Stem Cells -- Chapter 2A. Minireview of Stem Cell, Study Models & Effect of Trace Elements -- Chapter 3. Use of Stem Cells for Drug Screening -- Chapter4. Tissue Differentiation of ESC into Lung Cells & Functional Validation -- Chapter 5. Validation of Lung Stem Cell Niche -- Chapter 6. Model Organisms in Science & Research -- Chapter 7. Models for Studies in Regenerative Medicine -- Chapter 8 Role of Progenitors in Pulmonary Fibrosis and Asthma -- Chapter 9. Some Concepts in Studies of Kidney Regeneration -- Chapter 10. Ethics in Stem Cell Research -- Post Script. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
The information given in this book tries to capture the essence of the sheer dynamicity of the cell along with useful tips on how to address critical rate limiting steps in the process of exploration and investigation of its capacity to regenerate, rebuild and replenish from within. The definitions of stem cells, stemness, and the niche concept continue to undergo revisions. In adult vertebrates, hematopoietic and some non-hematopoietic progenitors are synthesized within specialized niches of bone marrow. They migrate to designated tissues, and are either trans-differentiated or become quiescent and settle down. These form the stem cell niche reservoir in all tissues. Not only the primary hematopoietic tissue but all organs and tissues are also capable of generating progenitors which are either synthesized from these migrants or are direct recruits from other tissues. In the niches, the cells settle down and await their turn to either make more clones like themselves or differentiate and mobilize in an exigency. Thus progenitors are important reserves, to be multiplied and deployed or travel as important message bearing molecules via blood as circulating progenitors which can home to their allocated destinations. Upon reaching, specific integrins and selectins help them “dock” and “port” and they may be reprogrammed to induce further differentiation and help repopulate the denuded tissue. In pulmonary fibrosis and asthma, progenitors from both systemic circulation and local stem cell niches have been found to participate in the myriad ramifications of repair, replacement and regeneration of lost or diseased tissue. Whether they are lung specific or global in origin and role remain to be explored. Research tools, fundamental concepts, techniques, methodologies and standard operating protocols and animal models and human extrapolations, have been discussed in a concise way along with detailed description and discussion on the appropriate rationale to introduce the subject to the casual reader and provide valuable tactical information to the specialist in Regenerative Medicine. I sincerely hope you enjoy the work and appreciate the hard work that has gone into designing and executing elegant experiments by many researchers in the field. The branch is multi-disciplinary and I hope that the readers will not be limited to biologists alone. . |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Life sciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Cytokines. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Growth factors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Stem cells. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Molecular ecology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Animal models in research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Biology |
| General subdivision |
Technique. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Life Sciences. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Stem Cells. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Molecular Ecology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Cytokines and Growth Factors. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Biological Techniques. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Animal Models. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Printed edition: |
| International Standard Book Number |
9788132220527 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/978-81-322-2053-4">http://dx.doi.org/10.1007/978-81-322-2053-4</a> |
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ZDB-2-SBL |
