MARC details
| 000 -LEADER |
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| fixed length control field |
04090nam a22004935i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-319-18326-8 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20160405112903.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
150609s2015 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783319183268 |
| -- |
978-3-319-18326-8 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-319-18326-8 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
R-RZ |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MBGR |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED000000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
610 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Life Extension |
| Medium |
[electronic resource] : |
| Remainder of title |
Lessons from Drosophila / |
| Statement of responsibility, etc |
edited by Alexander M. Vaiserman, Alexey A. Moskalev, Elena G. Pasyukova. |
| 264 #1 - |
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| -- |
Cham : |
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Springer International Publishing : |
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Imprint: Springer, |
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2015. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
VIII, 353 p. 49 illus., 26 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - |
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text |
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txt |
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rdacontent |
| 337 ## - |
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computer |
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c |
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rdamedia |
| 338 ## - |
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online resource |
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cr |
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rdacarrier |
| 347 ## - |
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text file |
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PDF |
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rda |
| 490 1# - SERIES STATEMENT |
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| Series statement |
Healthy Ageing and Longevity, |
| International Standard Serial Number |
2199-9007 ; |
| Volume number/sequential designation |
3 |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Preface -- SECTION I: Genetic regulation of longevity -- Mutations and quantitative genetic variation: lessons from Drosophila -- Modulation of Drosophila lifespan by neuronal genes -- Life span, stress resistance and age-dependent transcriptome dynamics in fruit flies with constitutive and conditional overexpression of GADD45 -- Superoxide dismutase over-expression and the mitochondrial unfolded protein response -- Effect of Wolbachia infection on aging and longevity-associated genes in Drosophila -- SECTION II: Drosophila models for aging-associated diseases -- Skeletal muscle homeostasis and aging -- Drosophila models of cardiac disease -- Genetic modulation of cardiac functional aging -- Functional links between circadian clocks, redox state and aging in Drosophila -- Drosophila models in therapeutic drug discovery -- SECTION III: Life-extending treatments -- Phytochemicals with lifespan extension effect in Drosophila -- Life extension in Drosophila by inhibitors of histone deacetylases -- Drosophila healthspan extension using dietary manipulation -- The effect of the artificial atmosphere on the flies’ longevity -- Effects of several mild stresses applied in adults on aging and longevity -- Life extension via stage-specific drug interventions in Drosophila -- Index. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in biogerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecular and cellular processes that underlie aging process, and it can perhaps provide new therapeutic targets for the treatment of age-related disorders in humans. Drosophila models have been developed for a large variety of aging-related processes and diseases, and this book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process. Themes of healthspan, life extension and longevity-associated genes emerge in this collation of international research on Drosophila that is of relevance to geriatrics and gerontology, animal genetics and genomics, and biomedicine. This fascinating, illustrated book will be of interest to a wide audience, ranging from academic researchers to the general reader. . |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Geriatrics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Animal genetics. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Biomedicine general. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Animal Genetics and Genomics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Geriatrics/Gerontology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Vaiserman, Alexander M. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Moskalev, Alexey A. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Pasyukova, Elena G. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Printed edition: |
| International Standard Book Number |
9783319183251 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
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| Uniform title |
Healthy Ageing and Longevity, |
| -- |
2199-9007 ; |
| Volume number/sequential designation |
3 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/978-3-319-18326-8">http://dx.doi.org/10.1007/978-3-319-18326-8</a> |
| 912 ## - |
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ZDB-2-SBL |
