MARC details
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03585nam a22005175i 4500 |
| 001 - CONTROL NUMBER |
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978-3-7091-1232-8 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20160405112940.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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150706s2015 au | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783709112328 |
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978-3-7091-1232-8 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-7091-1232-8 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QH588.S83 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
PSAK |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
SCI017000 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
SCI049000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
571.6 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Stem Cell Aging: Mechanisms, Consequences, Rejuvenation |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Hartmut Geiger, Heinrich Jasper, Maria Carolina Florian. |
| 264 #1 - |
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Vienna : |
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Springer Vienna : |
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Imprint: Springer, |
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2015. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
XI, 354 p. 33 illus., 32 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - |
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text |
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txt |
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rdacontent |
| 337 ## - |
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computer |
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c |
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rdamedia |
| 338 ## - |
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online resource |
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cr |
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rdacarrier |
| 347 ## - |
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text file |
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PDF |
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rda |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Introduction -- Stem cells, aging and longevity (overview) -- General mechanisms of stem cell aging (overview) -- Mechanisms of Stem Cell Aging in Model Organisms -- Yeast: Chronological aging -- Divisional aging -- Primarily germline -- stem cell aging -- Drosophila: Male germ line -- Female germ line -- Somatic stem cells (stress and regulation of hematopoietic precursors, intestinal stem cell aging and regulation). Zebrafish -- Mechanisms of Stem Cell Aging in Mammalian Tissues.-Hematopoietic (Mouse/Human) -- Skin (Mouse/Human) -- Intestine (Mouse/Human) -- Muscle (Mouse/Human) -- Neuronal Tissues (Mouse/Human) -- Diseases of Aging and Stem Cells -- Chronic Myeloid Leukemia and Aging of Hematopoietic Stem Cells (Mouse/Human) -- Wound Healing Repair and Aging of Skin Stem Cells (Mouse/Human) -- Stem Cell Rejuvenation Muscle -- Hematopoietic -- Neuronal. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems, and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Life sciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Cancer research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Hematology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Stem cells. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Life Sciences. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Stem Cells. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Cancer Research. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Immunology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Hematology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Geiger, Hartmut. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Jasper, Heinrich. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Florian, Maria Carolina. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Printed edition: |
| International Standard Book Number |
9783709112311 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/978-3-7091-1232-8">http://dx.doi.org/10.1007/978-3-7091-1232-8</a> |
| 912 ## - |
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ZDB-2-SBL |
