Primary Aldosteronism [electronic resource] : Molecular Genetics, Endocrinology, and Translational Medicine / edited by Per Hellman.
Material type: TextPublisher: New York, NY : Springer New York : Imprint: Springer, 2014Description: XI, 233 p. 25 illus., 17 illus. in color. online resourceContent type:- text
- computer
- online resource
- 9781493905096
- 611.01816 23
- 599.935 23
- RB155-155.8
- QH431
Item type | Current library | Call number | URL | Status | Notes | Date due | Barcode |
---|---|---|---|---|---|---|---|
e-Books | SARVAJNA LIBRARY, UHS, BAGALKOT | 611.01816 (Browse shelf(Opens below)) | Link to resource | Available | Click on the URL to access eBook | EB643 |
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611.01816 The Genetics of Obesity | 611.01816 Molecular Aspects of Botulinum Neurotoxin | 611.01816 Clinical Applications of Botulinum Neurotoxin | 611.01816 Primary Aldosteronism | 611.01816 Ion/Molecule Attachment Reactions: Mass Spectrometry | 611.01816 Protein NMR | 611.01816 Molecular Genetics of Pediatric Orthopaedic Disorders |
Introduction -- Primary Aldosteronism: Molecular Mechanisms and Diagnosis -- Epidemiology and need for screening -- Low renin hypertension -- Molecular derangements in sporadic primary aldosteronism -- From genetic abnormalities to pathophysiological mechanisms -- Familial hyperaldosteronism type I -- Familial hyperaldosteronism type II -- Familial hyperaldosteronism type III -- The Aldosterone-renin ratio – role and problems -- Confirmatory testing for Primary Aldosteronism -- Radiological imaging of adrenocortical tumors -- Aldosterone and cardiovascular disease -- Quality of life aspects of primary aldosteronism -- Medical treatment of primary aldosteronism -- Surgical treatment of primary aldosteronism -- Index.
Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene – KCNJ5 – in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.
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