000			03354nam a22005175i 4500
001			978-94-017-9235-6
003			DE-He213
005			20160405110702.0
007			cr nn 008mamaa
008			141024s2014 ne | s |||| 0|eng d
020			_a9789401792356 _9978-94-017-9235-6
024	7		_a10.1007/978-94-017-9235-6 _2doi
050		4	_aR-RZ
072		7	_aMBGR _2bicssc
072		7	_aMED000000 _2bisacsh
082	0	4	_a610 _223
100	1		_aEvgen'ev, Michael B. _eauthor.
245	1	0	_aHeat Shock Proteins and Whole Body Adaptation to Extreme Environments _h[electronic resource] / _cby Michael B. Evgen'ev, David G. Garbuz, Olga G. Zatsepina.
264		1	_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2014.
300			_aXVII, 218 p. 47 illus., 38 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aIntroduction -- The discovery of heat shock response system and major groups of heat shock proteins -- Molecular functions of heat shock proteins -- Regulation of heat shock genes expression -- Heat shock proteins and adaptation to variable and extreme environments -- Different trends in the evolution of heat shock genes systems.- The role of mobile elements in the evolution and function of Hsps systems -- Fine tuning of the HSR in various organisms -- Experimental modulation of heat shock response -- Glossary.
520			_aFor many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. The investigation of ecological and geographical variation in HSPs expression, begun by Evgen’ev and colleagues is now widespread. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. They also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, the authors describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.
650		0	_aMedicine.
650		0	_aLife sciences.
650		0	_aProteins.
650		0	_aCell biology.
650		0	_aCell physiology.
650	1	4	_aBiomedicine.
650	2	4	_aBiomedicine general.
650	2	4	_aLife Sciences, general.
650	2	4	_aCell Biology.
650	2	4	_aProtein Science.
650	2	4	_aCell Physiology.
700	1		_aGarbuz, David G. _eauthor.
700	1		_aZatsepina, Olga G. _eauthor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789401792349
856	4	0	_uhttp://dx.doi.org/10.1007/978-94-017-9235-6
912			_aZDB-2-SBL
999			_c3220 _d3220