000 03375nam a22005055i 4500
001 978-3-319-16438-0
003 DE-He213
005 20160405112856.0
007 cr nn 008mamaa
008 150808s2015 gw | s |||| 0|eng d
020 _a9783319164380
_9978-3-319-16438-0
024 7 _a10.1007/978-3-319-16438-0
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
245 1 0 _aSex and Gender Differences in Infection and Treatments for Infectious Diseases
_h[electronic resource] /
_cedited by Sabra L. Klein, Craig W. Roberts.
250 _a1st ed. 2015.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aX, 400 p. 21 illus., 18 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aSection 1 Genes hormones and immunity -- Sex difference in the immune response -- Sex chromosomes and immune function -- Sex and sex hormone mediated differences in wound healing -- Immunology of pregnancy and systemic consequences -- Sex differences in metabolism and pharmacokinetics -- Section 2 Infectious diseases and treatments -- HIV infection and responses to antiretroviral therapies -- Influenza virus infection and vaccination -- Hemorrhagic fever viruses and antiviral therapies -- Tuberculosis diagnosis and treatment -- Respiratory bacterial infection and treatments -- Outcome of bacterial and viral infections and vaccinations in neonates -- Sexually transmitted bacterial infection in women -- Lyme disease diagnosis and treatment -- Protozoan and helminth infections and treatments.
520 _aThis book provides an overview of the underlying sex-based and hormone-based differences in immunity, wound healing and pharmacokinetics, while also exploring how pregnancy affects immunity. The second part of the book shows, for the first time in a single volume, the growing number of infectious diseases for which sex and gender differences are noted, identifies common as well as distinct mechanisms mediating these differences and illustrates how responses to treatments might differ between the sexes. The awareness that males and females differ in their response to specific pathogens as well as to treatments for infectious diseases may yield sex-specific personalized treatments. This book will be of interest to basic scientists and clinicians in the fields of microbiology, immunology and pharmacology. Individuals working in academia, government and industry will also benefit from the information presented.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aPharmacology.
650 0 _aInfectious diseases.
650 0 _aMicrobiology.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aInfectious Diseases.
650 2 4 _aMicrobiology.
650 2 4 _aPharmacology/Toxicology.
700 1 _aKlein, Sabra L.
_eeditor.
700 1 _aRoberts, Craig W.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319164373
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-16438-0
912 _aZDB-2-SBL
999 _c4020
_d4020