000 | 03250nam a22004815i 4500 | ||
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001 | 978-3-319-16537-0 | ||
003 | DE-He213 | ||
005 | 20160405112857.0 | ||
007 | cr nn 008mamaa | ||
008 | 150420s2015 gw | s |||| 0|eng d | ||
020 |
_a9783319165370 _9978-3-319-16537-0 |
||
024 | 7 |
_a10.1007/978-3-319-16537-0 _2doi |
|
050 | 4 | _aRC261-271 | |
072 | 7 |
_aMJCL _2bicssc |
|
072 | 7 |
_aMED062000 _2bisacsh |
|
082 | 0 | 4 |
_a614.5999 _223 |
245 | 1 | 0 |
_aStem Cell Biology in Neoplasms of the Central Nervous System _h[electronic resource] / _cedited by Moneeb Ehtesham. |
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2015. |
|
300 |
_aXIII, 190 p. 16 illus., 15 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v853 |
|
505 | 0 | _aRegulation of Subventricular Zone-Derived Cells Migration in the Adult Brain -- The SVC and Its Relationship to Stem Cell Based Neuro-oncogenesis. - Isolation and characterization of stem cells for human central nervous system malignancies. - The role of stem cells in pediatric central nervous system malignancies. - Laboratory models for central nervous system tumor stem cell research. - Radiation Therapy for Glioma Stem Cells -- Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma -- Immunobiology and Immunotherapeutic targeting of glioma stem cells -- Emerging strategies for the treatment of tumor stem cells in central nervous system malignancies. | |
520 | _aThis volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aCancer research. | |
650 | 0 | _aNeurosciences. | |
650 | 0 | _aStem cells. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aCancer Research. |
650 | 2 | 4 | _aStem Cells. |
650 | 2 | 4 | _aNeurosciences. |
700 | 1 |
_aEhtesham, Moneeb. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783319165363 |
830 | 0 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v853 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-319-16537-0 |
912 | _aZDB-2-SBL | ||
999 |
_c4023 _d4023 |