000 | 03667nam a22005535i 4500 | ||
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001 | 978-3-319-17305-4 | ||
003 | DE-He213 | ||
005 | 20160405112859.0 | ||
007 | cr nn 008mamaa | ||
008 | 150610s2015 gw | s |||| 0|eng d | ||
020 |
_a9783319173054 _9978-3-319-17305-4 |
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024 | 7 |
_a10.1007/978-3-319-17305-4 _2doi |
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050 | 4 | _aRB155-155.8 | |
050 | 4 | _aQH431 | |
072 | 7 |
_aMFN _2bicssc |
|
072 | 7 |
_aMED107000 _2bisacsh |
|
082 | 0 | 4 |
_a611.01816 _223 |
082 | 0 | 4 |
_a599.935 _223 |
245 | 1 | 0 |
_aRNA and DNA Diagnostics _h[electronic resource] / _cedited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski. |
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2015. |
|
300 |
_aX, 349 p. 124 illus., 78 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aRNA Technologies, _x2197-9731 |
|
505 | 0 | _aElectrochemical Biosensors for miRNA Detection -- Electrochemical Detection of RNA.- DNA and PNA probes for DNA Detection in Electroanalytical Systems -- DNA for Non-Nucleic Acid Sensing -- Aptamers in Oncotherapy -- Genotyping of Single Nucleotide Polymorphism -- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA -- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics -- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures -- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods -- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics -- Mechanochemical Sensing.- Microarrays as Research Tools and Diagnostic Devices -- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.- Single-molecule strategies for DNA and RNA diagnostics -- Detection and Assessment of microRNA Expression in Human Disease. | |
520 | _aThe aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman’s famous statement “What I cannot create, I do not understand.”. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aHuman genetics. | |
650 | 0 | _aMolecular biology. | |
650 | 0 | _aBiotechnology. | |
650 | 0 | _aNucleic acids. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aHuman Genetics. |
650 | 2 | 4 | _aNucleic Acid Chemistry. |
650 | 2 | 4 | _aMolecular Medicine. |
650 | 2 | 4 | _aBiotechnology. |
700 | 1 |
_aErdmann, Volker A. _eeditor. |
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700 | 1 |
_aJurga, Stefan. _eeditor. |
|
700 | 1 |
_aBarciszewski, Jan. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783319173047 |
830 | 0 |
_aRNA Technologies, _x2197-9731 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-319-17305-4 |
912 | _aZDB-2-SBL | ||
999 |
_c4034 _d4034 |