000 03788nam a22004695i 4500
001 978-3-319-18392-3
003 DE-He213
005 20160405112903.0
007 cr nn 008mamaa
008 150827s2015 gw | s |||| 0|eng d
020 _a9783319183923
_9978-3-319-18392-3
024 7 _a10.1007/978-3-319-18392-3
_2doi
050 4 _aQP34-38
072 7 _aMFG
_2bicssc
072 7 _aMED075000
_2bisacsh
082 0 4 _a612
_223
245 1 4 _aThe Vertebrate Blood-Gas Barrier in Health and Disease
_h[electronic resource] :
_bStructure, Development and Remodeling /
_cedited by Andrew N. Makanya.
250 _a1st ed. 2015.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aXIV, 243 p. 55 illus., 23 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aChapter 1 Generalities of gas diffusion applied to the vertebrate blood-gas barriers -- Chapter 2 Morphological and morphometric properties of the blood-gas barrier: comparative perspectives -- Chapter 3 Prenatal and postnatal development of the vertebrate blood-gas barrier -- Chapter 4 Molecular mechanisms regulating the pulmonary blood-gas barrier (BGB) -- Chapter 5 Barrier enhancing signals -- Chapter 6 Trans-barrier ion and fluid transport -- Chapter 7 Stress failure of the pulmonary blood-gas barrier -- Chapter 8 The lung endothelial barrier in acute inflammation -- Chapter 9 Lung transplantation and the blood-gas-barrier -- Chapter 10 Stereological studies on transient gas-exchangers, with emphasis on the structure and function of the human placenta in normal and compromised pregnancies.
520 _aThis comprehensive volume on the blood-gas barrier (BGB) among vertebrates covers its structure and composition along with aspects of evolution, bioengineering, and morphometry. The book also discusses the embryological development of the BGB, including chronology of events and molecular control in vertebrates; modulation of the barrier function, including cyclic stretch-induced increases in alveolar epithelial permeability; mechanisms of lung vascular/epithelial permeability; transport mechanisms of the BGB, including sodium transport channels; factors affecting trans-barrier traffic of fluids, such as chronic elevation of pulmonary microvascular pressure; stress failure; regulation and repair in acute lung injury; chronic lung disease; and lung transportation. Ten authoritative chapters approach the blood-gas barrier holistically, from basic structure and development to pathology and treatment. Properties of the  BGB are discussed in the earlier chapters, followed by prenatal and post-natal development and mechanisms of the healthy BGB. The latter half of the book delves into the pathology of the  BGB, analyzing common afflictions and exploring options for treatment, including its alterations during lung transplantation. Intuitively structured and comprehensive, The Vertebrate Blood-Gas Barrier in Health and Disease is ideal for researchers and clinicians interested in pneumology and angiology.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 0 _aAngiology.
650 0 _aRespiratory organs
_xDiseases.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Physiology.
650 2 4 _aPneumology/Respiratory System.
650 2 4 _aAngiology.
700 1 _aMakanya, Andrew N.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319183916
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-18392-3
912 _aZDB-2-SBL
999 _c4054
_d4054