000 04392nam a22005175i 4500
001 978-3-319-20669-1
003 DE-He213
005 20160405112915.0
007 cr nn 008mamaa
008 151102s2015 gw | s |||| 0|eng d
020 _a9783319206691
_9978-3-319-20669-1
024 7 _a10.1007/978-3-319-20669-1
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
245 1 0 _aInfection and Cancer: Bi-Directorial Interactions
_h[electronic resource] /
_cedited by Michael R. Shurin, Yasmin Thanavala, Nahed Ismail.
250 _a1st ed. 2015.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aVI, 408 p. 15 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aInfection and Cancer: Multi-directorial relationship -- Part I Infection-associated cancers -- Human tumor viruses: A historical perspective -- Epidemiology of virus infection and human cancer -- Bacterial infections and cancer development -- Human protozoal infections and their potential for causing neoplasms -- An update on helminths in human carcinogenesis -- Infection-associated hematological malignancies -- Multiple infections and cancer: Etiology, mechanisms and implications in cancer control -- Inflammatory mechanisms of infection-associated cancer -- Part II Infection-associated cancers: Specific examples -- Helicobacter pylori: The cancer bug -- Oral infection, carcinogenesis and cancer -- Streptococcus Bovis and colorectal cancer -- Human papillomavirus-related cancers -- Part III Cancer-associated infections -- Infectious diseases in cancer patients: An overview -- Part IV Infection and cancer: Comorbid development -- Comorbid development of infection and cancer -- Part V Infection agent-based vectors for cancer therapy -- Bacterial cancer therapy: how patients might benefit from Salmonella infections -- Development of Salmonella-based cancer vaccines -- Harnessing the host immune response to infection - BCG immunotherapy for bladder cancer -- Index.
520 _aThis unique book summarizes current knowledge on co-development of infectious diseases and cancer. It provides an overview of the complex and unique role of the immune system, inflammation, tumor-mediated immunosuppression and infection-induced immunomodulation in cancer and infection progression.   Chapters are organized into themed parts, beginning with a look at the historical perspective of human tumor viruses, then aspects and examples of infection-related cancers and cancer-associated infections. The work discusses how cancer- and infection-associated immune responses interact in a bi-directorial fashion and how these interactions may evolve during both disease progression and in response to therapy. The phenomenon of independent development of cancer and infection in the same host, known as comorbid cancer-infection progression, is explored.   Understanding the complex pathways involved in the progression of infection and cancer will allow the prevention of the development of certain types of cancer, as well as advancing prophylactic anti-cancer vaccines. Readers of this work will discover innovative approaches for multidisciplinary projects, focusing on the design of original therapeutic modalities for cancer therapy. The book will therefore be particularly valuable to scholars interested in cancer immunology and researchers and clinicians in the field of basic and applied immunobiology and microbiology.  .
650 0 _aMedicine.
650 0 _aCancer research.
650 0 _aImmunology.
650 0 _aInfectious diseases.
650 0 _aMicrobiology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aInfectious Diseases.
650 2 4 _aImmunology.
650 2 4 _aMicrobiology.
700 1 _aShurin, Michael R.
_eeditor.
700 1 _aThanavala, Yasmin.
_eeditor.
700 1 _aIsmail, Nahed.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319206684
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-20669-1
912 _aZDB-2-SBL
999 _c4107
_d4107