000 04806nam a22004455i 4500
001 978-3-319-22822-8
003 DE-He213
005 20160405112923.0
007 cr nn 008mamaa
008 150930s2015 gw | s |||| 0|eng d
020 _a9783319228228
_9978-3-319-22822-8
024 7 _a10.1007/978-3-319-22822-8
_2doi
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
245 1 0 _aEpstein Barr Virus Volume 1
_h[electronic resource] :
_bOne Herpes Virus: Many Diseases /
_cedited by Christian Münz.
250 _a1st ed. 2015.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aVIII, 391 p. 50 illus., 38 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v390
505 0 _aPreface -- History -- Chap. 1 Why and How Epstein-Barr Virus was discovered 50 years ago - Anthony Epstein, University of Oxford, UK -- Chap. 2. Tumor associations of EBV – historical perspectives - George Klein, Karolinska Institutet, Stockholm, Sweden -- Chap. 3. EBV-specific immune response: early research and personal reminiscences – Denis J. Moss and Viviana P. Lutzky, Queensland Institute of Medical Research, Brisbane, Australia -- Virus genetics and epigenetics -- Chap. 4. Epstein Barr virus strain variation - Paul J. Farrell, Imperial College, London, UK -- Chap. 5. Chromatin Structure of Epstein-Barr Virus Latent Episomes  – Paul M. Lieberman, University of Pennsylvania, Philadelphia, USA -- Chap. 6. The epigenetic life cycle of Epstein-Barr virus - Wolfgang Hammerschmidt, Helmholtz Center Munich, Germany. Chap. 7. Epstein-Barr virus: from the detection of sequence polymorphisms to the recognition of viral types - Regina Feederle, Olaf Klinke, Anton Kutikhin, Remy Poirey, Ming-Han Tsai and Henri-Jacques Delecluse, German Cancer Research Center, Heidelberg, Germany -- Viral infection and associated diseases -- Chap. 8. EBV persistence – introducing the virus – David A. Thorley-Lawson, Tufts University, Boston, USA -- Chap. 9. Infectious mononucleosis – Samantha K. Dunmire, Kristin A. Hogquist and Henry H. Balfour, Jr., University of Minnesota, Minneapolis, USA -- Chap. 10. Primary immunodeficiencies associated with EBV disease - Jeffrey I. Cohen, National Institutes of Health, Bethesda, USA -- Chap. 11. Burkitt’s lymphoma – Rosemary Rochford  and Ann M. Moormann, University of Massachusetts, Worcester, and Upstate University of New York, Syracuse, USA -- Chap. 12. Contribution of the Epstein-Barr virus to the pathogenesis of Hodgkin lymphoma – Paul Murray and Andrew Bell, University of Birmingham, UK -- Chap. 13. The role of EBV in the pathogenesis of diffuse large B cell lymphoma – Jane A. Healy and Sandeep S. Dave, Duke University, Raleigh, USA -- Chap. 14. Nasopharyngeal carcinoma:  an evolving role for the Epstein Barr virus – Nancy Raab-Traub, University of North Carolina, Chapel Hill, USA.-Chap. 15. EBV and autoimmunity – Alberto Ascherio and Kassandra Munger, Harvard University, Boston, USA -- Index.
520 _aEpstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
650 0 _aMedicine.
650 0 _aVirology.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
700 1 _aMünz, Christian.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319228211
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v390
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-22822-8
912 _aZDB-2-SBL
999 _c4142
_d4142