000			02852nam a22004695i 4500
001			978-3-7091-1824-5
003			DE-He213
005			20160405112940.0
007			cr nn 008mamaa
008			150119s2015 au | s |||| 0|eng d
020			_a9783709118245 _9978-3-7091-1824-5
024	7		_a10.1007/978-3-7091-1824-5 _2doi
050		4	_aRC261-271
072		7	_aMJCL _2bicssc
072		7	_aMED062000 _2bisacsh
082	0	4	_a614.5999 _223
245	1	0	_aTumor Cell Metabolism _h[electronic resource] : _bPathways, Regulation and Biology / _cedited by Sybille Mazurek, Maria Shoshan.
264		1	_aVienna : _bSpringer Vienna : _bImprint: Springer, _c2015.
300			_aVIII, 374 p. 52 illus., 35 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aMetabolic Remodeling in Bioenergetic Disorders and Cancer -- Tumor Cell Complexity and Metabolic Flexibility -- Autophagy and Tumor Cell Metabolism.-Tumour Hypoxia and the Hypoxia-Inducible Transcription -- MYC Regulation of Metabolism and Cancer -- Pyruvate Kinase M2: A Metabolic Tuner -- Role of the Pentose Phosphate Pathway in Tumour Metabolism -- Enzymes of the Tumour Metabolome in Diagnostic Applications -- Contribution of pH Alterations to the Tumor Microenvironment -- Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis? The Relevance of the Mitochondrial H+-ATP Synthase -- Canceromics Studies Unravel Tumor’s Glutamine Addiction -- Essential Role of Mitochondria in Pyrimidine Metabolism -- Metabolic Fluxes in Cancer Metabolism -- Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer.
520			_aThe four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagnostic development, as well as for clinicians and oncologists.
650		0	_aMedicine.
650		0	_aCancer research.
650		0	_aMolecular biology.
650		0	_aOncology.
650	1	4	_aBiomedicine.
650	2	4	_aCancer Research.
650	2	4	_aMolecular Medicine.
650	2	4	_aOncology.
700	1		_aMazurek, Sybille. _eeditor.
700	1		_aShoshan, Maria. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783709118238
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-7091-1824-5
912			_aZDB-2-SBL
999			_c4214 _d4214