000 03947nam a22005535i 4500
001 978-94-017-9514-2
003 DE-He213
005 20160405113012.0
007 cr nn 008mamaa
008 141215s2015 ne | s |||| 0|eng d
020 _a9789401795142
_9978-94-017-9514-2
024 7 _a10.1007/978-94-017-9514-2
_2doi
050 4 _aQH301-705
072 7 _aPSA
_2bicssc
072 7 _aSCI086000
_2bisacsh
072 7 _aSCI064000
_2bisacsh
082 0 4 _a570
_223
245 1 0 _aSystems and Synthetic Biology
_h[electronic resource] /
_cedited by Vikram Singh, Pawan K. Dhar.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2015.
300 _aXI, 385 p. 114 illus., 75 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aIntroduction to Systems Biology -- Why Systems Biology Can Promote a New Way of Thinking -- Modelling Methodologies for Systems Biology -- In silico Identification of Eukaryotic Promoters -- Hill Equation in Modeling Transcriptional Regulation -- Molecular Modeling -- Complex Networks and Systems Biology -- Systems Biology of Infectious Diseases -- Systems Pharmacology and Pharmacogenomics for Drug Discovery and Development -- Switching Mechanism in the p53 Regulatory Network -- Systems Biology of Micro RNA -- A Brief Introduction to Synthetic Biology -- DNA Structure and Promoter Engineering -- Synchronous Sequential Computations with Biomolecular Reactions -- Designing Zinc Finger Proteins for Applications in Synthetic Biology -- Synthetic Biology for the Development of Biodrugs & Designer Crops and the Emerging Governance Issues -- Recent Advancement of Emerging Tools in Synthetic Biology for the Designing and Characterization of Genetic Circuits -- Metabolic Engineering of Microorganisms for Biosynthesis of Antibiotics -- DNA Origami: What, How and Where -- Making Synthetic Proteins from Non-coding DNA -- Engineering Biological Systems: A Brief Overview.
520 _aThis textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section deals with the systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section describes the engineering concepts and design strategies of biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell. Finally, the book offers expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists.
650 0 _aLife sciences.
650 0 _aBiochemical engineering.
650 0 _aBioinformatics.
650 0 _aSystems biology.
650 0 _aBiomathematics.
650 0 _aBiological systems.
650 0 _aBiomedical engineering.
650 1 4 _aLife Sciences.
650 2 4 _aSystems Biology.
650 2 4 _aBiomedical Engineering.
650 2 4 _aBiological Networks, Systems Biology.
650 2 4 _aBiochemical Engineering.
650 2 4 _aMathematical and Computational Biology.
650 2 4 _aComputational Biology/Bioinformatics.
700 1 _aSingh, Vikram.
_eeditor.
700 1 _aDhar, Pawan K.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789401795135
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-017-9514-2
912 _aZDB-2-SBL
999 _c4338
_d4338